icon-physicians-largeFrancis J. O’Donnell, D.O., Neurologist

Physician Bio

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Dr. O’Donnell is a Board Certified Neurologist specializing in headache treatment and research. Dr. O’Donnell, was born and raised in northern New Jersey where he attended St. Peter’s Preparatory School. Following high school graduation Dr. O’Donnell attended Lehigh University in Bethlehem, Pennsylvania where he received his Bachelor’s Degree and graduated Magna Cum Laude. Dr. O’Donnell attended Medical School at Kirksville College of Osteopathic Medicine in Kirksville, Missouri where he again graduated with high honors. Dr. O’Donnell completed his Internship at Doctor’s Hospital and his Residency at OSU Hospital both in Columbus, Ohio. While at OSU Hospital Dr. O’Donnell served as chief resident and started the OSU Headache Clinic.

As a clinical professor in the Department of Neurology at OSU Dr. O’Donnell developed an interest in Behavioral Medicine and began to design clinical research protocols in this area of study. Since joining Ortho Neuro in 1991 Dr. O’Donnell has become a clinical professor at Ohio University. This has allowed for collaboration with Ken Holroyd, Ph.D. in the Department of Psychology, one of the leading international experts on conservative behavioral treatment for headache. Dr. O’Donnell has designed and participated in drug and non-pharmacologic studies sponsored by the National Institute of Health attempting to determine the benefits of these treatments for tension and migraine headache sufferers. Dr. O’Donnell receives grant/research support from and serves on the speakers bureau for Abbot, Glaxo Wellcome, Merck, Pharmacia and Astra Zeneca companies.

Dr. O’Donnell was elected by his peers for inclusion in Best Doctors in America® from 2009 to 2017.

Dr. O’Donnell is the co-director of The Headache Management and Research Project and has published numerous papers presented at regional, national and international scientific meetings. He is an organizer and director for the Ohio State Headache Association and a member of the Central Ohio neurologic Society, the American Association for the Study of Headache and the Ohio and American Osteopathic Societies. Dr. O’Donnell resides in Westerville, Ohio.He enjoys running, fishing and playing golf. He still roots hard for the New York sports teams, but is an avid Ohio State, Chris Perry, Columbus Clipper, Crew and Blue Jackets fan.

  • Board Certification
    American College of Osteopathic Neurology and Psychiatry, Certificate #456, 05-26-99
  • Undergraduate
    Lehigh University, Bethlehem, Pennsylvania; B.A.
  • Medical School
    Kirksville College of Osteopathic Medicine, Kirksville, Missouri; D.O.
  • Residency
    Ohio State University Hospital, Columbus, Ohio; Neurology

Ratings and Comments

4.5 out of 5 (10 comments)


No regrets for choosing OrthoNeuro. Will be in on Friday for results of the MRI. Everyone was polite, cheerful & friendly. Thank you all.


Love this specific office!!


Very friendly & professional staff.


Nice & friendly!


Good place.


Great experience and I feel that with the care of the doctor I will get better again soon.


Love Roberta (Front Desk).


Helpful and concerned.


Everyone here is incredibly nice!


The front desk was especially patient with my Mom — which one might expect, but not find as often as you’d hope. This was very important, and made her feel more comfortable with an uncomfortable experience.